Wrath: Weapon Rune Word - Diablo 2
Wrath is a Missile Weapons only Weapon Rune Word which is generally overlooked by players since it doesn't offer any +Enhanced Damage like other Rune Words such as Faith. Overlooking this Rune Word would be a mistake, however, since it comes with Crushing Blow which does a % of the monsters total HP in damage--making +Enhanced Damage way less useful anyway.
Additionally, Wrath comes with huge damage bonuses to Demons and Undead, which are the majority of enemies you'll be fighting anyway. Ontop of these bonuses Wrath also has a Decrepify proc (increases damage taken by the enemy) along with Cannot be Frozen which will free up a ring slot since you won't need to use Ravenfrost anymore.
Keep in mind that all Rune Words you create will retain any pre-existing bonuses found on the item. If you find a 'Superior' piece of armor with +Enhanced Defense, a Superior Weapon with +Enhanced Damage or a Helm/Weapon that has +Skill bonuses for a certain class, all of these will remain on the final Rune Word that is created. It's also possible to 'ebug' a piece of Ethereal Armor that you find which will increase the Defense bonuses by 50%, check out my Ebugging Guide for more information.
Farming High Runes: Out of all locations in the game one stands above the rest for farming specifically High Runes, the Countess during Act 1. The Countess has a guaranteed chance to always drop a High Rune and can even drop more than one. Check out my The Countess Farming Guide for more information.
Required Runes: Pul -- Lum -- Ber -- Mal
Level Req: 63
Other Req: Ladder Only
Slots: Missile Weapons (Bows & Crossbows)
30% Chance To Cast Level 1 Decrepify On Striking
5% Chance To Cast Level 10 Life Tap On Striking
+375% Damage To Demons
+100 To Attack Rating Against Demons
+250-300% Damage To Undead (varies)
Adds 85-120 Magic Damage
Adds 41-240 Lightning Damage
20% Chance of Crushing Blow
Prevent Monster Heal
+10 To Energy
Cannot Be Frozen