Edge: Weapon Rune Word - Diablo 2
Edge is a rather unique Rune Word and probably more commonly used on a Mule character for the "Reduce All Vendor Prices" than it is on a character you plan on actually playing. Some Amazons may use Edge until they're high enough level for Harmony or Melody but aside from that the only class or build that would benefit a lot is a Summon Necromancer or Summoner Druid.
The built in Thorns Aura will be great for their minions since they take a lot of hits and since this Rune Word can only go in Missile Weapons, it's well suited for a caster.
Keep in mind that all Rune Words you create will retain any pre-existing bonuses found on the item. If you find a 'Superior' piece of armor with +Enhanced Defense, a Superior Weapon with +Enhanced Damage or a Helm/Weapon that has +Skill bonuses for a certain class, all of these will remain on the final Rune Word that is created. It's also possible to 'ebug' a piece of Ethereal Armor that you find which will increase the Defense bonuses by 50%, check out my Ebugging Guide for more information.
Farming High Runes: Out of all locations in the game one stands above the rest for farming specifically High Runes, the Countess during Act 1. The Countess has a guaranteed chance to always drop a High Rune and can even drop more than one. Check out my The Countess Farming Guide for more information.
Required Runes: Tir -- Tal -- Amn
Level Req: 23
Other Req: Ladder Only
Slots: Missile Weapons (Bows & Crossbows)
Level 15 Thorns Aura When Equipped
+35% Increased Attack Speed
+320-380% Damage To Demons (varies)
+280% Damage To Undead
+75 Poison Damage Over 5 Seconds
7% Life Stolen Per Hit
Prevent Monster Heal
+5-10 To All Attributes (varies)
+2 To Mana After Each Kill
Reduces All Vendor Prices 15%